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POT1 抗体

This anti-POT1 antibody is a 兔 多克隆 antibody detecting POT1 in WB 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6568518
发货至: 中国

Quick Overview for POT1 抗体 (ABIN6568518)

抗原

See all POT1 抗体
POT1 (Protection of Telomeres 1 (POT1))

适用

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  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 28
  • 3

克隆类型

  • 28
  • 3
多克隆

标记

  • 21
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This POT1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human POT1

    亚型

    IgG
  • 应用备注

    WB 1:200 - 1:2000 IHC 1:50 - 1:200

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    POT1 (Protection of Telomeres 1 (POT1))

    别名

    POT1

    背景

    Synonyms: DKFZP586D211,hPot 1,hPot1,POT 1,POT1,POT1 like telomere end-binding protein,POT1 protection of telomeres 1 homolog,POT1-like telomere end-binding protein,POTE1,Protection of telomeres 1,Protection of telomeres 1 homolog (S. pombe),Protection of telomeres protein 1

    Background: This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.

    分子量

    Observed_MW: 75kDa

    Calculated_MW: 60kDa/71kDa

    基因ID

    25913

    UniProt

    Q9NUX5

    途径

    Cell Division Cycle, Telomere Maintenance
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